Soluble CD30 levels as a diagnostic marker for bronchiolitis obliterans syndrome following human lung transplantation
نویسندگان
چکیده
منابع مشابه
Bronchiolitis obliterans following lung transplantation.
Bronchiolitis obliterans syndrome (BOS) is the main and late chronic complication after lung transplantation. It remains a major impediment to long-term outcome. Unfortunately, the survival rate of lung transplant recipients lags behind that of other organ transplant recipients, and BOS accounts for more than 30% of all mortality after the third year following lung transplantation. Most recent ...
متن کاملBronchiolitis Obliterans Syndrome (BOS) Following Lung Transplant.
The main change seen with BOS is scarring of the small airways of transplanted lung(s). This scarring leads to narrowing of the airways, limiting airflow with loss of lung function. Early after the onset of BOS, a person may not have any symptoms, but will develop breathlessness and chronic cough as BOS gets worse. There are different stages of BOS based on lung function results. Some people de...
متن کاملCytolytic therapy for the bronchiolitis obliterans syndrome complicating lung transplantation.
UNLABELLED The bronchiolitis obliterans syndrome (BOS) is the major cause of late morbidity and mortality after lung transplant (LTx). Previous studies suggest cytolytic therapy may be effective for the BOS but this therapy has not been proved effective or safe. METHOD A retrospective study of a predetermined treatment regimen to determine if the rate of fall in FEV1 can be reduced by cortico...
متن کاملBronchiolitis Obliterans After Lung Transplantation
ing lung transplantation is 71%, and 46% of trans¬ plant recipients will survive at least 5 years.1 Al¬ though infections, medication-related adverse events, and malignancies remain important compli¬ cations, prolonged survival is limited predominantly by bronchiolitis obliterans (RO), a condition that was associated with transplantation more than a decade ago.25 Data suggest that at least 50% ...
متن کاملCalcineurin inhibitors in bronchiolitis obliterans syndrome following stem cell transplantation.
Bronchiolitis obliterans is a complication after allogeneic haematopoietic stem cell transplantation (HSCT). Management of bronchiolitis obliterans comprises intensive immunosuppression, but treatment response is poor. We investigated the effect of cyclosporine A (CsA), tacrolimus (FK506), methylprednisolone (mPRED), mycophenolate mofetil (MMF) and everolimus on the proliferation of primary lun...
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ژورنال
عنوان ژورنال: Transplant Immunology
سال: 2008
ISSN: 0966-3274
DOI: 10.1016/j.trim.2007.07.007